January 23, 2014 
It’s been a few years since I’ve worked on medication adherence solutions. It seems to have become a big focus again in the industry both with the Medicare Star Ratings program and with all the emphasis on waste.
- Can Digital Health Help Crack One Of Healthcare’s Hardest Nuts?
- The Next Killer App To Cut Healthcare Costs
- Medicine Is Most Expensive When It’s Not Taken At All
- Thinking Outside the Pillbox
- The Importance Of Medication Adherence Whitepaper
As I started thinking about adherence, I thought it would be good to create a list of solutions and vendors. I couldn’t find one anywhere on the web. So, here’s my initial list of almost 100 companies.
I’ll make this a dynamic list so please comment or send me suggestions to add.
Here’s some old posts on adherence that I think are still relevant here:
- 15 Things To Know About Prescription Non-Adherence
- Improving Statin Adherence
- Non-Adherence Infographic
I’ve divided the list of solutions and vendors into the following:
Devices
- Adherence Solutions LLC – develop programs to create alliances between different players, sell Dose-Alert which is a smart pill bottle cap, and provide a mobile tool
- AdhereTech – smart pill bottles
- Automated Security Alert – medication dispensers to complement their medical alert system
- Biodose – electronic tray for monitoring time and day of use
- CleverCap – smart cap for pill bottle
- Didit – manual tracking device that attaches to a pill bottle
- DoseCue – smart pill bottle
- eCap – electronic compliance monitor
- ePill – medication reminder devices
- eTect – biocompatible tag on the pill with connectivity and a mobile solution focused on clinical trial adherence
- iRemember – smart pill bottle cap with voice reminder and smart phone synching
- MedCenter – monthly organizer and reminder system
- Med-E-Lert – automated pill dispenser
- MedMinder – automated pill dispenser
- MedVantx – medication sampling at the physician’s office
- Proteus – smart pill technology
- Quand Medical – uses Near Field Communications and mobile to do medication management and reminders
- SMRxT – smart pill bottle
- TalkingRx – audio device attached to pill bottle
- uBox – smart pillbox
- Vitality GlowCap – smart pill bottle with communication programs
Mobile / Digital
- 2Comply – patient portal with web coaching
- ActualMeds – online medication management for consumers, caregivers, and providers
- AI Cure Technologies – digital health solution
- AssistMed – web and mobile based adherence solutions
- Ayogo – social games and apps to improve engagement and adherence
- CareSpeak – mobile solution
- Care4Today – two-way messaging platform, app, and website
- CellepathicRx – mobile solution
- CloudMetRx – cloud based solution to help caregivers with medication management
- Dosecast – mobile medication management and pill reminder
- GenieMD – mobile medication management and reminders as part of broader solution
- iPharmacy – mobile pill identifier, medication guide, and reminder app
- Mango Health – mobile medication management with gamification and incentives
- Medacheck – mobile reminder system that incorporates caregivers
- MedCoach – mobile medication management and pill reminder
- MedHelper – medication compliance and tracking app
- mHealthCoach – reminder based solution creating a digital support system
- Mscripts – mobile solution
- MyMeds – mobile and web medication management and pill reminder solution
- MyMedSchedule – mobile Rx management tool with reminder service
- Nightingale – mobile solutions for reminders, engaging your physician, and notifying your caregivers
- PillBoxie – mobile medication management and reminder app
- PillManager – mobile medication management and pill reminder
- PillMonitor – mobile medication reminders and logs
- PillPhone – mobile phone solution with biometric authentication
- Prescribe Wellness – automated, digital interventions
- RightScript – platform to manage prescriptions through mobile reminders that connect patients, caretakers, practitioners, and health plans
- RxCase Minder – mobile medication management
- RxNetwork – mobile medication management and reminders with rewards
- Quintiles – building digitally, connected communities
- Virtusa – multi-dimensional interventions across the patient’s journey
Platform
- Adheris – adherence suite and advanced analytics (just acquired Catalina Health) [note: they are owned by inVentiv Health who I work for]
- Avanter – an adherence program for pharmacies in Argentina
- Capzule – pill reminders as part of PHR
- Dr. First – embedded tools into EHR
- HealthPrize – platform with gamification, incentives, education, and communications
- LDM Group – suite of compliance products
- McKesson – sampling, coaching, coupons, and messaging
- MediSafe – mobile medication management app and adherence platform
- MedPal Health Solutions – platform for medication adherence solutions
- MedSimple – medication management, pill reminders, coupons, and PAP programs
- mHealthCoach – care collaboration platform using machine learning to personalize communications
- Tavie – virtual nurse for improving adherence focused on several conditions
Communications
- Ateb – multi-channel communication programs for pharmacies
- Atlantis Healthcare – custom adherence solutions
- Eliza – multi-channel communication programs
- Intelecare – multi-channel adherence communications
- MemoText – messaging platform
- Patient Empowerment Program – medication adherence program for pharmacies
- Pleio – adherence solutions for the first 100-days (when most people stop taking medications)
- Silverlink – multi-channel communication programs [note: this is the company that I used to work for and still use]
- Varolii (now Nuance) – multi-channel communication programs
- Voxiva – web and text messaging solution
- West – multi-channel communication programs
Big Data
- Allazo Health – predictive model to create individualized targeting
- Express Scripts – ScreenRx predictive model
- FICO – medication adherence score
- Optum Drug Adherence Index – risk scoring predictive model
- RxAnte – advanced analytics
Tools / Enablers
- 5th Finger – assessment and personalization tools
- GNS Healthcare – using data and predictive models to identify targets and fuel intervention programs
- HumanCare Systems – creating patient and caregiver support solutions
- Insignia (PAM) – measure of patient activation for segmentation and scoring
- MedMonk – help pharmacists obtain funding for patients who can’t afford their out-of-pocket pharmaceutical expenses
- MedSked – low tech, high impact labeling solution
- Merck Adherence Estimator – screening tool available as a widget or online at Merck Engage
- NaviNet – communications network to enable adherence
- NCPA – toolkit and ROI calculator for pharmacies
- ScriptYourFuture – tools and text reminders
- Walgreens API – an application programming interface for developers to use to connect their adherence solutions to Walgreens
Medicare focused
- Dovetail – pharmacist led programs including MTM, in-home visits, and telephonic coaching (focused on Star Ratings)
- Mirixa – incorporated into the MTM program
- Outcomes – data and tools as part of their MTM solution
- Pharm MD – Medicare STARS program
Condition specific
- GeckoCap – adherence offering for kids with asthma
- MyRefillRx – mobile adherence app focused on high blood pressure
Packaging
- Colbert Packaging – compliance packaging solution
- DailyMed by Walgreens – packaging
- Helping Hand – smart packaging
- Med-In-Touch – medication adherence solutions in the area of packaging and mobile
- MTS – medication adherence packaging solutions
Pharma
- 90Ten Healthcare – providing adherence programs in 23 countries
- TrialCard – voucher and co-pay programs for consumers to stop Rx abandonment
- Triplefin – customized programs for pharma brand managers
- Adherence Engagement Platform – a Pfizer program of adherence materials and tools (I couldn’t find it online only in hard copy)
- RS Associate – a company working with manufacturers in India
- Rx.com – MTM, pre-edit messaging at the POS, and print-on-demand messaging at the pharmacy
International (recommendations send to me without English sites)
- Observia (France)
What other companies am I missing? Send them to me directly or add them in the comments section here. Thanks.
Enabling Healthy Decisions 
Dear Mr. Van Antwerp,
Thank you for recognizing us in your article for our MedSked. Would you be so kind to add the word – high-Impact to the right of “low tech.” Technology is not a requirement for effectiveness or to work; take a look at the post-it note. Not much technology there but very effective and being used by millions.
MedSked is an effective adherence tool that is innovative, easy to use, and cost effective, and was designed with the concept of the post-it note – low-tech, high impact. It is being purchased and used globally by some of the world’s largest pharmaceutical companies.
Thank you.
Kind regards,
Anthony Londino
President
Med-Con Technologies
We have a brand new software App called C3Healthlink – connect…communicate…collaborate – that has a medication therapy management (MTM) system built in. MTM is an integral piece of health and wellness data that is driving outcomes based healthcare – r
George;
Agadia Systems, Inc. is rolling out RxContinuum, an adherence solution that focuses on managing the intervention with patients/prescribers. It puts control of the identification rules and the interventions right on the users desktop. Also has the CMS Star Ratings rules pre-built to generate alerts and enable Plans to address these patient safety and adherence situations to improve their ratings. Be glad to share more with you if you want to reach out.
Hi Mr. Van Antwerp, would be great to add my company, HealthID Profile, to the list under Mobile/Digital. We believe the 3 areas our product focuses on (medication management with reminders, chronic disease management and the ability to share personal health info in either an emergency or routine doctor visit) offer our customers additional value because all of their personal health info is located in one simple solution. Our website is http://www.healthid.com. Thanks so much!
There is also a smart dispenser from Sweden on the market: Medimi
Producer: MedicPen ( http://medicpen.com/ )
Hi there,
Good article. Just wanted to drop by and ask if you know anything about a little defunct company called “Arcadia Healthcare” who used to owned the proprietary rights to “DailyMed” before it was sold to Walgreens for pennies on a dollar?
Is Arcadia Healthcare involved in any of the medication adherence solutions? Just weird to me that they used to own DailyMed and then after selling off, they continued to hire for new positions but the company was suppose to be bankrupt?
As one person commented to me, the retail pharmacies, PBMs, and specialty pharmacies along with many payers also have adherence programs. Here, I was focused on vendors providing services to them.